- Rochester Museum & Science Center - Located at 657 East Ave. and they house a collection of 1.2 million artifacts. The museum is focused on educating the Rochester community of all ages in science, technology and local history.
- Strasenburgh Planetarium - Located right next to the RMSC building, this planetarium is known world-wide for its innovative Star Theater which seats 225 and runs daily shows with regular special events. It was the first of its kind to be fully computer automated.
- Strong National Museum of Play - Located conveniently off of the 490 highway at 1 Manhattan Square Dr, The Strong is a worldwide recognized educational institution housing interactive collections related to the study and exploration of play. It is home to the Woodbury School, the International Center for History of Electronic Games, the National Toy Hall of Fame, the World Video Game Hall of Fame, the Brian Sutton-Smith Library and Archives of Play, and the American Journal of Play.
- Susan B. Anthony House - the home of Susan B. Anthony for forty years and where she was arrested for attempting to vote in the 1872 presidential election. Now a learning center and museum of Rochester's contribution to women's rights located at 19 Madison St.
- George Eastman Museum - a National Historic Landmark located at 900 east Ave., it is the estate of Kodak's founder, George Eastman and dedicated to photograph and motion picture archives as well as film preservation and photograph conservation. It houses the 500-seat Dryden Theatre which plays daily showings of classic motion pictures.
- Genesee Country Village & Museum - 19th-century living history museum just 20 miles from Rochester in Mumford, NY. Over 600 acres containing actual architecture from the time, the John L. Wehle Gallery of Sporting Art, the Genesee Country Nature Center, the Carriage Museum, the Silver Baseball Park and the Heirloom Gardens.
Parks & Resorts:
- Monroe County Parks - Park Department oversees over twenty parks in the Rochester area providing a wide array of outdoor opportunities from camping, nature, zoological, horticultural, historical and geological features.
- Bristol Mountain Resort - Skiing and winter resort located near Canandaigua in the Finger Lakes with 35 runs and over 2,000 ft. elevation.
- Seabreeze Amusement Park - family-friendly historic amusement park located right on Lake Ontario in the Rochester suburb of Irondequoit. Home to the Jack Rabbit, America's oldest continuously operating roller coaster.
- Seneca Park Zoo - an almost 16-acre zoo since 1894 located right in Rochester housing over 90 different species.
- Cumming Nature Center - 900-acre environmental preserve run by RMSC located in Naples, NY down in the Finger Lake region. Education facility features over six miles of trails offering service-learning opportunities.
- Blue Cross Arena at the War Memorial - multi-purpose indoor arena featuring concerts and events. It is home to three Rochester sports teams; the Amerks (AHL hockey), Razorsharks (PBL basketball) and Knighthawks (NLL indoor lacrosse).
- Frontier Field - baseball stadium for the Rochester Red Wings in downtown Rochester.
- Capelli Sport Stadium - home to Rochester's USL soccer team, the Rhinos and host to many local high school sporting championships.
- Main Street Armory - multi-purpose arena located at 900 East Main St.
- GEVA Theatre - regional professional theater company of Rochester located at 75 Woodbury Blvd.
- Rochester Auditorium Theatre - providing opportunities to all people to experience, understand and enjoy the best of the performing arts. Volunteer, non-profit organization since 1957, Rochester Broadway Theatre League is located at 885 East Main St.
- Eastman Theatre - the largest performance stage in Rochester with state-of-the-art acoustics located at 26 Gibbs St. It is home to the Rochester Philharmonic Orchestra.
- CMAC - The Constellation Brands - Marvin Sands Performing Arts Center is an amphitheater style outdoor concert venue located near Canandaigua in the Finger Lakes Region and features regularly sold out top names in music.
- The Marketplace Mall - Outlet mall located in Henrietta, south of Rochester.
- The Mall at Greece Ridge - Mall located in Greece, west of Rochester.
- Eastview Mall - Largest local, high end mall located in Victor, southeast of Rochester.
- Waterloo Premium Outlets - outlet mall of 100 stores featuring designer and brand name accessories, jewelry, gifts, clothing and specialty items located in Waterloo of the Finger Lakes region southeast of Rochester.
- City of Rochester Public Market - city run public market located at 280 N. Union St. offering fresh local produce and other items every Tuesday, Thursday and Saturday.
- Lilac Festival - Free spring festival of Highland Parks' lilac flowers, hundreds of musical acts, wine & chocolate tasting, craft brews, parade, kiddie rides and more.
- Jazz Festival - Early summer concert series of multiple genres from all over the world featuring over a thousand performers at 19 venues across Rochester.
- Monroe County Fair - Mid-summer's celebration of the area's advancements in agriculture and related technology in Spencerport.
- Fringe Festival - Early autumn showcase of creativity in theatre, comedy, dance and music.
- Corn Hill Arts Festival - Free summer festival featuring artists, music, beer and wine gardens all throughout Rochester's historic Corn Hill neighborhood.
- Park Ave Summer Arts Festival - Late summer exhibit along over a mile on Park Ave in downtown Rochester of over 350 artists, craftspeople, entertainers, food and shopping.
- Fairport Canal Days - Largest event on Rochester's historic Erie Canal with culinary, visual and artisan goods to kick off the summer.
- Polar Plunge - Rochester's annual winter event benefiting the Special Olympics.
- Webster Fireman's Carnival - Area's largest parade followed by a weekend of carnival activities benefiting and representing local fire fighters from departments as far away as Toronto, Canada to Watkins Glen, NY below the Finger Lakes.